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Health and Nutrition

Fasting and Ghrelin – Fasting 29

Ghrelin is the so-called hunger hormone. It was purified from rat stomach in 1999 and subsequently cloned. It binds to growth hormone (GH) secretagogue receptor, which strongly stimulates GH. So, for all you people who thought that eating makes you gain lean tissue, it is actually the opposite. Nothing turns off GH like food. Of...

Why you’re always hungry – Fasting 28

How do you reign in hunger? We all think that eating more will prevent hunger, but is this really true? This is what is behind the advice to eat 6 or 7 times a day. If you can prevent hunger, then you may be able to make better food choices, or eat less. On the surface,...

The Evidence for Caloric Restriction

There are many people, highly educated and believing themselves intelligent, that say that all diets come down to calories. So, any diet that works automatically comes down to cutting calories. It seems to be a fallback position of many academics and researchers and others who tend not to live in the real world. They say...

Diabetes prevention and Reversal – T2D31

Diabetes associations repeatedly tell the story that type 2 diabetes is a chronic and progressive disease. It is inevitable, like getting older. As much as we would like to stop the process, it is impossible. There is no hope to change its course. It cannot be prevented and cannot be reversed. But multiple studies and...

Meat Kills! Maybe, possibly….

Recent headlines are filled with proclamations that 'Meat Kills!' Nothing sells newspapers like the old chestnuts - meat kills!, saturated fat is bad! Let's take a quick look at this most recent study see if we can draw some conclusions. The study was called 'Association of Animal and Plant Protein Intake with All-Cause and Cause-Specfic Mortality',...

Keith Harmon – "Fasting builds, not burns muscle"

No matter how often I write about this, I always get questions/ accusations that I'm lying that fasting actually causes muscle loss, usually from people who never fast. But the evidence is just not there. Terry Crews, former NFL star recently discussed how intermittent fasting keeps him in shape. When Hugh Jackman needed to bulk...

X Marks the Spot – T2D 30

Triglycerides and coronary disease Gaizano et al. Circulation. 1997;96:2520-2525 Why should we care about high triglycerides? Doctors always obsess about LDL cholesterol and barely a word is heard about triglycerides, yet high blood triglycerides strongly and independently predict cardiovascular disease, almost as powerfully as LDL. Hypertriglyceridemia increases the risk of heart disease by as much...

Hyperinsulinemia and Hypertriglyceridemia T2D 29

The liver lies at the nexus of metabolism and nutrient flow, particularly carbohydrates and proteins. Situated immediately downstream from absorptive surface of the intestines, those nutrients enter the blood in the portal circulation and pass directly to the liver. The major exception is dietary fat, which is absorbed as chylomicrons directly into the lymphatic system...

Who needs to avoid Fat Bombs and BPC?

Does eating extra fat via Fat Bombs and Bullet Proof Coffee make you fat? Here's the short answer. Yes and no. If you are slender, then eating fat will not make you fat. If you are obese/ overweight then yes, eating more fat will make you fat. Let me explain. The answer, of course, has...

Sugar and Obesity – Fructose 3

One of the most intuitive facts in nutrition is that eating lots of sugar makes you fat. I don't really think that there is all that much disagreement on this point. There is certainly some argument about why this is true. The calories people claim that this is because it is a source of empty...

Fructose, Fatty Liver, and insulin resistance – T2D 28

Fructose and fatty liver Fructose is even more strongly linked to obesity and diabetes than glucose. From a nutritional standpoint, neither fructose nor glucose contains essential nutrients. As a sweetener, both are similar. Yet fructose is particularly malevolent to human health compared to glucose due to its unique metabolism within the body. Glucose and fructose...

Fructose1 – T2D 27

The Deadly Effects of Fructose In 2009, Dr. Robert Lustig, a pediatric endocrinologist at the University of California, San Francisco delivered a ninety minute lecture entitled “Sugar: The Bitter Truth”. It was posted on YouTube as part of the university’s medical education series. Then a funny thing happened. It went viral. It was not a...