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Hormonal Obesity

The Atkins Decline – Hormonal Obesity Part XX

The Atkins revolution was well and truly underway by the mid 2000s.  Millions of people around the world were following the Low-Carbohydrate lifestyle.  Burger King introduced lettuce wrapped burgers to reduce the carb content.  Everybody seemed to know somebody who was on the diet and had lost a lot of weight.  The possibility of permanently...

The Atkins Revolution – Hormonal Obesity part XIX

Short term studies of the Atkins low carbohydrate diet were very encouraging.  Not only were patients losing more weight, but their metabolic profiles were improved compared to the low fat diets of years past.  Millions of people were taking a low carbohydrate lifestyle, and seeming to enjoy the benefits.  By the mid 2000's, Dr. Atkins...

The Atkins Onslaught – Hormonal Obesity XVIII

The low carbohydrate diet long preceded the infamous Dr. Atkins.  Jean Anthelme Brillat-Savarin (1755 -1826) wrote the influential textbook “The Physiology of Taste” in 1825. Sometimes considered the father of the low carbohydrate diet, he wrote: “The second of the chief causes of obesity is the floury and starchy substances which man makes the prime...

The Role of Fibre II – Hormonal Obesity XVII

The main role of fibre is that of an anti-nutrient.  By various mechanisms such as bulking and viscosity the absorption of nutrient may be slowed in the GI tract.  This is especially beneficial in the absorption of glucose which tends to cause insulin to spike with meals.  This study illustrates the effect of fibre. Thirteen...

The Role of Fibre I – Hormonal Obesity XVI

Fibre is the non digestible part of food, usually a carbohydrate that our bodies cannot break down and absorb.  They pass through our system largely unchanged.  There are 2 types of fiber - soluble and insoluble based on whether it can be dissolved in water.  Plant foods often contain varying amounts of both types of...

Good Carbohydrates, Bad Carbohydrates – Hormonal Obesity XV

There is controversy surrounding whether carbohydrates are good or bad.  The low-carb movement (the Atkins onslaught) of the late 1990s and 2000s did much to focus attention on the role of carbohydrates in obesity.  Are carbohydrates good or bad?  Opinions are all over the place.  Many low carb advocates suggest to avoid all carbohydrates altogether....

Time Dependence of Obesity – Hormonal Obesity XIV

Weight gain has a clear and obvious time dependence.  People tend to gain weight slowly, over years or even decades.  Many people start off as a skinny teenager (age 20), but gradually gain 1-2 pounds per year.  This isn’t so bad, but after 40 years they may be up to 80 pounds overweight (age 60)....

The Perils of Snacking – Hormonal Obesity XIII

  50 years ago, there was a near universal belief that snacking was bad for us.  Your grandmother would say “It makes you fat”, or “You’ll ruin your dinner”.  Back then, obesity was not such a big problem, so maybe they knew something.  But then we changed our minds.  To review the previous post click...

Prevention of Resistance – Hormonal Obesity XII

One of the keys to high insulin levels lies in insulin resistance.  To start the Hormonal Obesity series – click here. Insulin resistance leads to high insulin levels.  It also appears that high levels of insulin also leads to insulin resistance in a vicious cycle.  How does the body normally defends against insulin resistance? High...

The New Science of Diabesity – Hormonal Obesity XI

Diabesity is so-named because of the close association of obesity and diabetes (type 2).  Obesity typically comes first and type 2 diabetes comes later.  This leads many to conclude that obesity causes diabetes.  On the surface, this seems reasonable, since the two often co-exist.    Where it becomes more difficult, however, is when people try to explain...

Insulin Causes Insulin Resistance – Hormonal Obesity X

Insulin resistance plays a large role in increasing insulin levels.  Increasing insulin levels tend to drive weight gain and obesity.  Continuing from the previous post, we continue our exploration of the hormonal obesity theory.  To start Hormonal Obesity part I, click here. The question we need to answer is this.  What causes Insulin Resistance?  From...

Drug Tolerance – Hormonal Obesity IX

We are discussing insulin resistance and how it develops.  Clues from other biological systems suggests that looking at the agent itself may be important in resistance. What about for drugs, particularly addictive drugs such as cocaine?  Resistance also develops, but the name is different. When a drug (say, cocaine) is taken initially there is usually an...